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Cell and Molecular Biology: Cancer Biology, PhD

Related programs.

Cell and Molecular Biology: Cell Biology, Physiology, and Metabolism, PhD
Cell and Molecular Biology: Developmental, Stem Cell, and Regenerative Biology, PhD
Cell and Molecular Biology: Gene Therapy and Vaccines, PhD
Cell and Molecular Biology: Genetics and Epigenetics, PhD
Cell and Molecular Biology: Microbiology, Virology, and Parasitology, PhD

Cell and Molecular Biology

The Cell and Molecular Biology Graduate Group (CAMB) is an interdisciplinary graduate program, providing rigorous training in modern cell and molecular biology, preparing students for leadership careers in biomedical research. Within this integrated program are six discipline areas: Cancer Biology ; Cell Biology, Physiology, and Metabolism ; Developmental, Stem Cell and Regenerative Biology ; Gene Therapy and Vaccines ; Genetics and Epigenetics ; and Microbiology, Virology and Parasitology . Program faculty include more than 300 scientists representing 35 departments from the Perelman School of Medicine, the Schools of Arts and Sciences, Dental Medicine, and Veterinary Medicine, Children’s Hospital of Philadelphia, the Wistar Institute and Fox Chase Cancer Center. The research efforts of these scientists are diverse in their focus, experimental system, methodology, and represent the leading edge of basic and translational biomedical science.

Students from colleges and universities around the nation and the world are enrolled in the program, selecting one discipline area based on their scientific interests, yet have access to the full breadth of curricular and research opportunities provided by this large and diverse program. Our students participate in core courses in cell and molecular biology, specialized coursework in one or more discipline areas, and original hypothesis-driven thesis research. Upon completion of the PhD, they pursue successful research careers at top academic institutions, in the biotech and pharmaceutical industries, and in other biomedicine-related career paths.

For more information: http://www.med.upenn.edu/camb/

Cancer Biology

The Program in Cancer Biology provides students focused training in a number of areas of cancer biology ranging from basic mechanisms to translational applications. Program faculty conduct research in DNA repair, epigenetics, metabolic pathways, the tumor microenvironment, cancer cell autonomous processes, cancer genetics and cancer immunology. Students take core molecular and cell biology courses, biostatistics course and elective courses in cancer biology and undertake three laboratory rotations of their choosing. Students have the opportunity to take grant writing courses, present in research-in-progress seminars, engage in networking opportunities, mentor undergraduates and high school students in Philadelphia as well as participate in outreach opportunities.

For more information: https://www.med.upenn.edu/camb/cb.html

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The degree and major requirements displayed are intended as a guide for students entering in the Fall of 2024 and later. Students should consult with their academic program regarding final certifications and requirements for graduation.

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Integrated Biomedical Sciences (IBS)

Cancer biology phd program.

The GW Cancer Biology PhD program is designed to equip the next generation of researchers with the knowledge, research training and leadership skills necessary to foster progress in the prevention, detection and treatment of cancer. The PhD program provides research training in areas reflecting GW faculty expertise, which includes the study of cancer signaling and checkpoint inhibitors, cancer immunology and immunotherapy, and molecular mechanisms of oncogenesis and metastasis, cancer genomics and epigenetics and the tumor microenvironment.

The GW Cancer Center (GWCC) brings together cancer research, clinical cancer care, and cancer control/prevention and outreach initiatives at GW, and offers students a range of exciting research programs, seminars and retreats. Researcher labs are located on the 8th floor of the contemporary Science and Engineering Hall, in Ross Hall and other locations. An important focus for the Cancer Center is to address prominent health disparities in breast, cervical, colorectal, pancreatic, liver and prostate cancers faced by communities in the District of Columbia. Students have access to cutting-edge core facilities for flow cytometry, imaging, and computational biology as well as the Cell Enhancement and Technologies for Immunotherapy (CETI) lab , and state-of-the art GW Biorepository resource of biospecimens and clinical data to facilitate research on HIV/AIDS and cancer.

The GW Cancer Biology Training Program (supported by NIH T32 CA247756) is a prestigious dual basic/clinical mentorship program guided by expert cancer researchers and clinician investigators designed to prepare the next generation of outstanding cancer research scientists. The two-year program for predoctoral students and postdoctoral fellows includes courses and workshops as well as a discovery research project leading to an independent research career. Students apply for this program at the end of their first year, with their mentor and cancer-related research.

The PhD in Cancer Biology begins with the interdisciplinary coursework in molecular, cellular, and systems biology and research rotations offered through GW’s Integrated Biomedical Sciences curriculum . In the second and third semester students add a comprehensive introduction to the conceptual and experimental underpinnings of cancer biology. Further electives, career development coursework in scientific writing, oral communication, and research ethics and laboratory rotations are provided. Following required laboratory rotations, students complete a. grant-style qualifier and then work with their research advisor and the Graduate Program Directors to complete remaining Cancer Biology degree requirements, including the research dissertation.

Cancer Biology Courses:

CANC 8221: The Basic Science of Oncology CANC 8222: Molecular Oncology and Epigenetics CANC 8998: Advanced Reading and Research Seminar Course CANC 8999: Dissertation Research

Some Suggested Electives:

GENO 6237: Proteomics & Biomarkers CANC 8223: Cancer Immunology BIOC 6240: Next Gen Sequencing HSCI 6263: Biostatistics Clinical Translational Scientific Research (online)

Seminars/Journal Clubs:

The Cancer Biology seminar series held is held Thursday at 4 pm, and the monthly Tumor Board discussions held each Friday morning at 8 am. An annual Cancer Center Retreat is held in May. Faculty and trainees share interest groups (breast, prostate, ovarian cancer) as well as thematic meetings (Cancer Biology, Cancer Immunology, Cancer Engineering), to focus on common research interests.

Examples of Recent Cancer Biology PhD Dissertations:

Sulgi (John) Lee PhD. 2020, “Identification and Characterization of Tumor Specific Antigens in Pediatric Diffuse Midline Gliomas” Mentors: Javad Nazarian, Eric Villain. (Now Application Scientist at Namocell, Washington DC)

Eden Dejene, PhD 2020 “Regulation of Poly(A)-specific ribonuclease Activity by Reversible Lysine Acetylation”. Mentor: Edward Seto, Inducted into Bouchet Society, NCI supplement. (Now Associate Scientist, Abcam, United Kingdom)