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Thesis Nootropics vs Adderall: How They Work, Side Effects & Choosing if One is Right for You
When it comes to addressing common symptoms of ADHD, from inattention to hyperactivity , one of the most popular forms of treatments is the stimulant medication Adderall® . Like other stimulants, Adderall works by targeting brain chemicals like dopamine and norepinephrine to reduce symptoms of ADHD. It is available by prescription only.
A newer type of stimulant that is available without a prescription is Thesis nootropics , which contains ingredients like functional mushrooms, choline, vitamins, and adaptogens to enhance cognitive function. Though they are not recommended to treat any health condition, including ADHD, many people do use them to manage symptoms like inattention and hyperactivity to avoid the side effects associated with prescription stimulants like Adderall.
But do they work? This is what we’ll explore in the following article: which product is better for ADHD, the side effects of each, and alternative medications to consider.
ADHD Medication Overview
ADHD is a neurodevelopmental disorder that affects a person’s ability to focus, control impulses, and regulate their emotions. Medications are often a key component of ADHD treatment and there are several different types. They include:
- Stimulant Medications : Stimulant medications work by increasing the levels of certain neurotransmitters like dopamine and norepinephrine in the brain to improve attention and impulsive control. Examples include Adderall, Ritalin® , Concerta®, and Vvvanse® . These are the most commonly prescribed ADHD medications and are sometimes taken as needed.
- Non-Stimulant Medications : Though stimulants are the most common drugs for ADHD, in some cases, a doctor will prescribe non-stimulant ADHD meds if a patient doesn’t respond to stimulants or if side effects are too intense. Non-stimulant meds also target brain chemicals to control symptoms of ADHD, but these drugs tend to work slower than stimulants and are typically dosed for daily use. Examples include Strattera®, Intuniv®, and Kapvay®.
- Other Medications : In some cases, doctors may prescribe antidepressants, such as Wellbutrin®, tricyclic antidepressants, or serotonin-norepinephrine reuptake inhibitors (SNRIs) like Effexor® if the patient doesn’t respond to stimulants or non-stimulants. Alternatively, some individuals consider taking non-prescription homeopathic medications like Brillia to avoid the side effects associated with prescription drugs or to avoid having to increase the dosage of current prescription drugs. Brillia is designed to reduce symptoms associated with ADHD and anxiety without harsh, synthetic chemicals or harmful side effects, making it a suitable choice for those with co-occuring conditions.
Thesis Nootropics vs Adderall: Which is Better for ADHD?
Though nootropics like Thesis are sometimes referred to as “smart drugs” because of their ability to boost focus and cognitive function, they may not be as potent as prescription stimulant drugs like Adderall in reducing symptoms of ADHD. There are some distinct differences between their mechanisms of action, their safety profiles, and the research surrounding each.
The active ingredients in Thesis nootropics, which include functional mushrooms, vitamins, and herbal extracts are generally safe and gentle on the body, which could be appealing to those who have not responded well to prescription drugs like Adderall, which contains the chemical amphetamine. However, nutritional supplements like Thesis are not regulated by the FDA in the same way as prescription drugs, so questions remain surrounding their safety and efficacy.
How Thesis Nootropics Work to Boost Cognitive Function
According to the manufacturers of Thesis , the ingredients in their formulas work across “multiple brain pathways,” to support brain energy, optimize neurotransmitter status, improve cerebral circulation, and enhance neuroprotection. 1 Like many other supplements, Thesis is not intended to target the source of symptoms; rather the nutrients in their different blends can help the general function of the brain and improve overall well-being. This is different from medications, which target specific chemical imbalances in the brain to stop the instigation of symptoms altogether. Some of the research-backed nutrients include:
- Lion’s mane mushroom : May increase levels of brain derived neurotrophic factor (BDNF) to improve clarity and focus 2
- Vitamin B12 : May improve attention and mood 3
- Bacopa monnieri : May improve memory 4
- Tyrosine : May increase dopamine synthesis 5
- L-Phenylalanine : May reduce depressive symptoms 6
- Panax ginseng : May improve executive function (when combined with omega-3s) 7
What to Know About Adderall
First approved in 1996 , Adderall is a prescription drug consisting of amphetamine and dextroamphetamine, which are central nervous system stimulants that bind to dopamine and norepinephrine receptors in the brain. 8 This binding effect increases the levels of these neurotransmitters, which is thought to improve concentration and alertness while reducing hyperactivity and impulsivity.
Though Adderall and other stimulant medications are highly effective for many and typically a first-line treatment, this medication is associated with a number of side effects, including headache, upset stomach, and decreased appetite — which is one of the reasons many try to avoid using them to see if more gentle options can give the level of support that is adequate. Adderall is also notorious for being misused and abused by high school and college students due its reputation as a study aid and euphoria inducer.
Side Effects of Both
Though the side effects of Thesis nootropics are generally milder than those associated with Adderall, they should still be considered. Explore the side effects of both products below.
Thesis Nootropics Side Effects
Numerous Thesis reviewers have expressed satisfaction with the product, reporting no adverse effects. While some blends include caffeine, which can cause jitteriness or interfere with sleep, users have the option to exclude it. On the flip side, some reviewers have mentioned experiencing side effects such as nausea and insomnia 9 .
Thesis is also not suitable for children.
Adderall Side Effects
Adderall, like other stimulants, is known to cause a number of side effects in users. These side effects may go away on their own or you can work with your doctor to adjust your dosage or switch to another medication.
Side effects of Adderall include:
- Upset stomach
- Loss of appetite
- Weight loss
- Mood changes
- Nervousness
- Fast heart rate
Which Product is More Effective?
When it comes to Thesis vs Adderall for ADHD, reviews are mixed. Adderall seems to outshine Thesis in terms of efficacy, but it does come with a higher risk of more serious side effects.
Here is a sampling of the reviews of Thesis on TikTok and Reddit:
- Worked for a few hours, then downhill : TikTok user mikerapadas said: “Motivation [blend] provided me a real feeling of drive. I could feel myself being pulled towards my task and I felt little hints of extra optimism. But…it lasted only a few hours. After that came the negatives: mainly, I just felt less well overall; my temper was slightly more sensitive, and I could feel myself getting annoyed a lot more easily.” 10
- More focused, but poor sleep : Reddit user jamie_choo wrote: “Not sure if it's just a placebo effect but I do feel more focused throughout the day. However, I've been losing sleep in the last couple of days since my mind is way more active at night than usual.” 11
Reviews on Adderall are also mixed, but lean toward the positive when it comes to efficacy alone. Adderall has an average rating of 7.2 out of 10 from a total of 372 reviews On Drugs.com. Sixty-four percent of reviewers reported a positive experience, while 20 percent reported a negative experience . 12 Negative reviews of Adderall have more to do with the side effects than efficacy, with remarks that the medication caused rapid heart rate, stomach pains, anxiety , insomnia, hallucinations, and suicidal ideation . 13
Alternative ADHD Medications
If you’re looking for something safe and impactful to reduce ADHD symptoms, there are other options beyond nootropic supplements and prescription ADHD medication .
Brillia is one alternative option to consider. Free from harsh, synthetic chemicals and harmful side effects, Brillia is a clinically-proven non-prescription homeopathic medication that contains targeted antibodies to the S100B protein, a crucial regulator of various brain processes, both intracellular and extracellular. By modulating the activity of this protein, Brillia can effectively manage symptoms of ADHD and anxiety without causing side effects like drowsiness, nausea, decreased appetite, dependency, nor does it mask the personality in any way.
It's worth noting that Brillia does not disrupt blood chemistry, a common feature of stimulant medications like Adderall. In balancing the S100B protein Brillia also helps to normalize the levels of monoamines, including dopamine, norepinephrine, and serotonin, in different brain regions, mirroring the neurotransmitter targets of drugs like Adderall.
In contrast to dietary supplements like Thesis, Brillia adheres to rigorous FDA standards and regulations, encompassing quality, claims, and labeling. The product's active and inactive ingredients must undergo thorough review, and supporting evidence for its claims is required for sale in the United States. Backed by clinical evidence supporting its safety and efficacy, Brillia can be safely used by children as young as five and adults , without the need for an official diagnosis or medical supervision.
Brillia is also incredibly versatile. You can use the medication as an alternative to prescription medication or in conjunction with prescription medication to address lingering symptoms like anxiety (a common side effect of Adderall and other stimulant medications). Some users take Brillia with their prescription medication to avoid having to increase the dosage of their current meds, which also increases the likelihood of side effects.
If you choose to transition to Brillia from a prescription medication, we ask that you do so under the guidance of your doctor to ensure this path is right for you.
How to Choose Which One is Right for You
There is no single way to treat ADHD and what may work for you may not work as well for another person. Weighing the pros and cons of each option available is the best way to make an informed decision regarding your own care. At Brillia, we recommend starting with healthy lifestyle changes , including following a nutritious diet , getting enough sleep , controlling your screen time , and practicing mindfulness techniques regularly. These are all powerful factors that can make an impactful improvement in your symptoms and potentially help you avoid medications and supplements altogether.
If you need more support and choose to try Brillia , we ask that you find the dose that best meets your needs and remain consistent with your dosage while the product builds up in your system. Brillia is a gentle and cumulative product, and your body relies on a steady trickle of the active ingredient to get the best results. Most users see a result in 3-4 weeks, but it may take longer. If you need help finding the right dose, our Customer Care team is always available to offer guidance to ensure you experience the best results with Brillia. You’ll also have access to a wide community of Brillia users who can share tips and resources on how to make the most of your Brillia journey.
To explore other options on managing symptoms of ADHD with or without prescription medication, visit the Brillia(nce) Resource Center and learn how a holistic approach can help you develop the tools you need to control your symptoms long-term.
References: 1 https://takethesis.com/pages/science, 2 https://pubmed.ncbi.nlm.nih.gov/31118969/, 3 https://www.mdpi.com/2072-6643/14/7/1494, 4 https://pubmed.ncbi.nlm.nih.gov/20590480/, 5 https://pubmed.ncbi.nlm.nih.gov/30853567/, 6 https://pubmed.ncbi.nlm.nih.gov/380577/, 7 https://pubmed.ncbi.nlm.nih.gov/32847461/, 8 https://www.psycom.net/adderall-amphetamine, 9 https://www.reddit.com/r/Nootropics/comments/ru37qm/thesis_nootropics_review/, 10 https://www.tiktok.com/@mikerapadas/video/7251691048630603050, 11 https://www.reddit.com/r/Nootropics/comments/ru37qm/thesis_nootropics_review/, 12 https://www.drugs.com/comments/amphetamine-dextroamphetamine/adderall-for-attention-deficit-disorder.html, 13 https://www.drugs.com/comments/amphetamine-dextroamphetamine/adderall-xr-for-attention-deficit-disorder.html
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I Tried 4 Thesis Nootropic Blends (My 2024 Review)
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Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. Health and wellness celebrities have pushed it, causing a wave of popularity.
Do Thesis nootropics live up to the hype?
- Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
- Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
- Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
- Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
- Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
- Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.
Quick Verdict
Thesis has a range of suitable nootropic blends to cater to many needs.
However, our #1 nootropic of choice is NooCube. It’s designed for long-term brain changes, not just short-term boosts in mental performance.
What Is Thesis Nootropics?
Thesis Nootropics is a company that specializes in customized cognitive performance products. Dan Freed founded it in 2017.
Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.
This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.
The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.
Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.
The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.
Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.
Thesis Nootropics
Customized Blends For Cognitive Enhancement
Take the quiz and see which blends are right for you.
Thesis Nootropic Ingredients
Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.
The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .
The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.
Thesis Clarity Blend
Alpha gpc (speculative).
Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .
Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .
It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .
It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .
Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.
Lions Mane Mushroom (Speculative)
The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .
According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .
It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .
Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .
While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.
Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.
Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:
Camellia Sinensis Tea Leaf (Speculative)
Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.
Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.
Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .
The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.
I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.
Dihydroxyflavone
Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).
BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .
It enhanced memory formation in healthy rats and improved spatial memory in Alzheimer’s disease mouse models [14] .
Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .
This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.
Thesis Energy Blend Ingredients
Citicoline is commonly mentioned in relation to memory enhancement. Studies have shown that 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .
According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .
The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.
Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.
Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .
In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .
These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .
Thesis Energy contains 300 mg of mango leaf.
Theacrine is a purine alkaloid similar to caffeine. It is found in the Camellia kucha plant and is often included in dietary supplements.
Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .
Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .
It may enhance cognitive function and physical performance, either alone or in combination with caffeine [23] .
Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Theacrine manufacturers fund some of these studies.
Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.
N-Acetyl Cysteine
N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.
Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .
Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .
To confirm its benefits, the effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies [27] .
N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.
In human trials, a 600 – 2000 mg dose seems needed for cognitive benefits. Thesis Energy contains 500 mg, which is potentially underdosed.
Indian Trumpet Tree
Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .
Compared to a placebo, this supplementation improved episodic memory and numeric working memory. It also accelerated learning in location tasks.
However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.
The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.
Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.
This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.
L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .
It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.
While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.
It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .
According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.
Thesis Creativity Blend Ingredients
Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.
Agmatine Sulfate
Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.
Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .
It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.
In animal studies, agmatine sulfate has been shown to be safe and well-tolerated, with oral administration effectively increasing its levels in the brain [32] .
This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.
Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.
Panax Ginseng
Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .
It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .
Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .
Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.
Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.
Ashwagandha Root
Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .
It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .
Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .
It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.
Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.
Sceletium Tortuosum
Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .
Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .
Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .
The plant’s bioactive alkaloids are also being explored for commercial medicinal use.
The 25 mg dose in Thesis Creativity is the same as used within the human trials.
Thesis Motivation Blend Ingredients
L-phenylalanine.
L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.
Studies have shown that doses of up to 1200 mg show initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance develops over 2-4 months [44] .
In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .
However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .
Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.
Methylliberine
Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.
Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .
These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .
However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.
The 100 mg dose in Thesis Motivation aligns with the current research.
Vitamin B12 (Speculative)
Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.
Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .
There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .
B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.
Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.
Forskolin (Speculative)
Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.
Studies have shown that it restores nest-building and social behaviors in mice with Alzheimer’ s-like symptoms, reduces amyloid plaque deposition, and regulates brain inflammation [53] .
Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .
Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .
These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.
I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.
Artichoke (Speculative)
Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .
In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .
Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .
The 450 mg dose is well under the dose used in these studies.
Thesis Confidence Blend Ingredients
Saffron (speculative).
Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .
Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .
However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.
All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.
Magnesium Bisglycinate
Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .
However, its role in anxiety and mood disorders is less clear [62] .
Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .
Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .
500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.
Sage (Speculative)
Sage, also known as Salvia, has traditionally been known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .
This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.
However, this has not been replicated.
While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.
Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.
Sceletium Tortuosum (Speculative)
As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. The same 25 mg dose is used in human trials.
Magnolia Bark (Speculative)
Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.
Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .
The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.
Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .
These are rodent studies, so they cannot be extrapolated to humans. Regardless, they are included based on the mechanistic data and the theory that the 10 mg dose does the same thing in humans.
Ashwagandha Leaf & Root
The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.
Thesis Logic Blend Ingredients
Ginko biloba.
Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.
Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .
Clinical trials have shown it to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .
Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.
Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.
Theobromine
Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.
Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .
Further studies are needed to fully understand its impact on cognition.
Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .
However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .
More research is required to confirm theobromine’s cognitive and mood-related effects.
Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.
Phosphatidylserine
Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .
Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .
It is well absorbed in humans and crosses the blood-brain barrier.
Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated. Dosages ranging from 100 to 800 mg per day are advised for cognitive support [76] [77] .
Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.
High DHA Algae
DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.
DHA consumption improves adult cognitive abilities, especially when paired with eicosapentaenoic acid (EPA) [78] .
This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.
Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.
Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.
Triacetyluridine (Speculative)
Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .
The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).
Results indicated significant early improvement in depression symptoms.
Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.
Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.
Bacopa Monnieri
Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.
Studies have demonstrated that bacopa extract, specifically bacosides A and B, increases memory formation, recall, and cognitive function [80] .
It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.
Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.
Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . However, more research is needed to thoroughly grasp its usefulness across many cognitive domains.
Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.
Thesis Nootropics Price
Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:
- Subscription = $79
- One Time Purchase = $119
This is regardless of whether you purchase a personalized starter kit or build your own box.
You can’t buy them individually, either. You must purchase four boxes. When building your own, you can choose whether you want four of the same blend or mix and match.
They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.
Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.
Is Thesis Nootropics Really Personalized?
I went through the initial quiz to see how they “personalize” their nootropic stack.
Here is what they recommended me:
Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.
However, the fact they have multiple blends means people can experiment to find which works best for them.
I will say, though, that if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, and many are underdosed.
Benefits Of Thesis Nootropics
Multiple blends for different purposes.
To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.
Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.
Options For Stimulants Or Not
You can choose whether or not to include stimulants in your Thesis Blends. If you add the caffeine and L-theanine nootropic stack, the most potent synergistic brain booster, every blend will provide similar benefits.
However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.
My Experience With Thesis
Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.
I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.
The Logic and Clarity Blends had small positive effects on my concentration on mentally demanding tasks like writing, coaching, or podcasting.
If I were to continue taking Thesis, I’d opt for either of these two blends.
Who Is Thesis For?
Busy working professionals.
Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.
They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.
Creative Artists
For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can help break through creative blocks, foster innovative thinking, and maintain a heightened state of inspiration.
They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.
Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.
The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.
Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.
They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.
Coffee Haters
Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.
These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.
User Testimonials And Reviews
You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:
“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)
“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)
I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.
Thesis Side Effects
Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.
Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.
Thesis Alternatives
If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.
SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.
It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.
This brain supplement contains Lion’s Mane Extract, Citicoline, rhodiola rosea extract, L-theanine, Bacopa Monnieri, ginkgo biloba, and panax ginseng.
Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.
Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.
Read more in our Nooceptin review .
Mind Lab Pro
Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.
Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.
Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.
These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.
Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.
Our Mind Lab Pro review goes into great detail.
Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.
Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.
Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.
Our Braini review contains an in-depth breakdown.
Vyvamind is a nootropic supplement containing caffeine and L-theanine. It helps users focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.
Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.
This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.
Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.
Our Vyvamind review goes into great detail.
Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. It contains ingredients such as Bacopa Monnieri, L-tyrosine, and L-theanine.
These are well-known for their mental health advantages. However, several compounds, such as Huterzine-a and Alpha GPC, remain speculative without additional investigation.
NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.
Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.
Our detailed analysis can be found in our NooCube review .
Frequently Asked Questions
What is thesis nootropic and what does it do.
Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Depending on the blend chosen, users can expect improvements in focus, reduction in procrastination, stress management, and memory recall.
Does Thesis Work Like Adderall?
Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.
Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.
Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.
How Long Does It Take Thesis Nootropics To Work?
If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.
I’ve explored the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.
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- Iglesias-Carres, L., Bruno, A., D’Antuono, I., Linsalata, V., Cardinali, A., & Neilson, A. P. (2023). In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects. Journal of Functional Foods, 107, 105674.
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- Ayati, Z., Yang, G., Ayati, M. H., Emami, S. A., & Chang, D. (2020). Saffron for mild cognitive impairment and dementia: A systematic review and meta-analysis of randomised clinical trials. BMC Complementary Medicine and Therapies, 20, 1-10.
- Zhang, C., Hu, Q., Li, S., Dai, F., Qian, W., Hewlings, S., … & Wang, Y. (2022). A Magtein®, Magnesium L-Threonate,-Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults. Nutrients, 14(24), 5235.
- Boyle, N. B., Lawton, C., & Dye, L. (2017). The effects of magnesium supplementation on subjective anxiety and stress—a systematic review. Nutrients, 9(5), 429.
- Botturi, A., Ciappolino, V., Delvecchio, G., Boscutti, A., Viscardi, B., & Brambilla, P. (2020). The role and the effect of magnesium in mental disorders: a systematic review. Nutrients, 12(6), 1661.
- Phelan, D., Molero, P., Martinez-Gonzalez, M. A., & Molendijk, M. (2018). Magnesium and mood disorders: systematic review and meta-analysis. BJPsych open, 4(4), 167-179.
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- Lee, H. K., & Lee, U. J. (2015). Effects of Ethanol Extract from Magnolia Officinalis on Anxiety and Cognitive Function. The Journal of Internal Korean Medicine, 36(4), 507-517.
- Borgonetti, V., Governa, P., Manetti, F., Miraldi, E., Biagi, M., & Galeotti, N. (2021). A honokiol-enriched Magnolia officinalis Rehder & EH Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. Journal of Pharmacy and Pharmacology, 73(9), 1161-1168.
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Thesis Supplements: 2024 Review of These Cognitive Enhancers
A nyone suffering from a short attention span knows the drill—moments of productivity followed by (often longer) moments of distraction. Here’s the good news: Thesis offers personalized nootropics that claim to boost your brain power . But do these “smart pills” actually work?
In our Thesis supplements review, we’ll explore the various products. Learn all about the Thesis supplements ingredients, cognitive benefits, and potential side effects. Discover if these brain boosters are a good match for you!
Thesis Supplements Overview
So, what kind of supplements does Thesis offer? The simple answer is nootropics— substances that aim to improve your brain function , like memory and focus.
To be specific, each one of the Thesis supplements focuses on a key aspect of your cognitive function. Every product combines ingredients to provide a unique mental advantage, like boosting motivation, clarity, creativity, or energy.
About Thesis
Thesis was founded by Dan Freed in 2017 . Frustrated with his own challenges with focus and concentration, he wanted to create an over-the-counter solution.
His personal journey helped him establish the company; the team’s mission is to empower others to find the right combination of cognitive-enhancing ingredients. It’s all about customization, giving you the exact support your brain needs.
Better yet, the company also highlights customer education. It shares detailed information on the ingredients and their benefits—so you’ll understand exactly what you’re putting in your body.
Key Features
Now that we know about the company, let’s take a look at some perks that sets it apart from the competition:
- Personalized Recommendations: There are two ways that Thesis customizes your nootropic supplements. First, it provides a quiz that will help you pinpoint the right product for you. Then, it offers one-on-one coaching to help you optimize your blend even further.
- High-Quality Ingredients: Thesis takes a “seed to shelf” approach to its products. It takes care in choosing its suppliers, testing its ingredients in all product states, and packaging in clean environments using pharmaceutical-grade equipment.
- Excellent Customer Service: You can contact Thesis’ customer service in two ways: phone or email. Whatever you’re requesting or asking, their team is bound to answer you quickly.
Quick Verdict
Thesis Nootropics is an intriguing option for folks who wish to boost their brain power in a tailored way. Does the promise of customization lean a bit on the marketing side? Maybe. Yet, the one-on-one coaching, variety of blends, and top-notch ingredients make Thesis a solid choice for those aiming to enhance their mental performance.
>>Check the latest prices for Thesis supplements here
How Do Thesis Supplements Work?
Are Thesis supplements legit? Thesis nootropics are all about giving you brain-boosting solutions that fit your unique needs. Each specialized blend—designed to tackle different cognitive challenges—blends a different set of ingredients.
Customers like you will start by taking a quiz that dives into your brain chemistry, lifestyle, and what you hope to achieve. Based on the results, Thesis suggests a blend for you. Then, you can decide whether to subscribe or make a one-time purchase.
Thesis Supplements Reviews: Breakdown
Thesis offers six distinct nootropic blends designed to target specific aspects of cognitive function. Now, let’s start our reviews on Thesis supplements.
Thesis Clarity
Thesis Clarity is packed with alpha GPC—a chemical your body usually naturally produces—that may play a role in memory and learning [1]. That’s why Thesis paired its proprietary blend with lion’s mane mushrooms, which could help maintain your brain function and support memory [2].
Who Is Thesis Clarity Best For?
Do you suffer from brain fog, especially after lunch or a demanding work day? Clarity could be a great choice among Thesis nootropics. After all, it can help you concentrate better on your tasks throughout the day.
Who Should Avoid Thesis Clarity?
One of the ingredients in Thesis Clarity is caffeine. If you’re sensitive to stimulants, then you can try gentler Thesis blends instead.
User Reviews
If you’re curious about the effectiveness of Thesis supplements Reddit user r/myles92 said Clarity was the best Thesis supplement for ADHD in his opinion. According to him, this makes it much easier for him to take action and do things, instead of being stuck thinking about them [3].
On the other hand, r/empathic-researcher relayed that it made him a bit too energetic and reactive to stressful situations [4].
Thesis Logic
Thesis Logic combines eight ingredients to help support memory and promote deep thinking all day long. These include synapsa (a.k.a. bacopa monnieri) and ginkgo biloba—which may reduce stress, boost dopamine, and improve your memory [5][6].
Who Is Thesis Logic Best For?
Logic from Thesis is designed for people who require analytical skills. So, if you’re in fields like finance, engineering, or scientific research, it might come in handy. The supplement could help improve your problem-solving and decision-making skills .
Who Should Avoid Thesis Logic?
Just in case you’re easily affected by caffeine, look for another Thesis alternative to Logic since it features this stimulant.
R/crafty_fox9 thought Logic worked well, helping her do some of her complicated work [7]. She reported that her brain was on hyperdrive, although it did make her a bit moody and drained by the end of the day [7].
Thesis Energy
Thesis Energy is built to give you sustained energy —a buildup that’s meant to last over six hours to keep your motivation and concentration levels elevated. It showcases theacrine that could energize you while sharpening your mental performance but with a lower risk of crashing than caffeine alone [8].
Who Is Thesis Energy Best For?
Feeling tired at midday and tired of drinking cup after cup of coffee? Afternoon slumps, fatigue, brain fog by the end of the day—if you suffer from any of these issues, Thesis Energy may be a good option for you.
Who Should Avoid Thesis Energy?
Some reviewers said Thesis Energy causes more anxiety than they usually experience. Plus, if stimulants make you feel jittery, you could try the caffeine-free version instead.
Redditor r/leftylucy88 wrote that Energy is especially useful for days when she hasn't gotten enough sleep the night before. She also said it didn’t feel like Adderall or Modafinil, as the supplement is much more subtle and sustained [9].
However, others wrote that the ingredients were a bit strong. For instance, Reddit user r/missycritter said that she felt anxious, nauseous, and dizzy after taking Energy [10].
Thesis Motivation
The Motivation supplement is designed to level up your drive, focus, and productivity . One of the ingredients, l-theanine, could encourage you to stay on track by improving your attention and memory skills [11]. This might make you feel more motivated and mentally empowered throughout your work day.
Who Is Thesis Motivation Best For?
Do you struggle with procrastination and a lack of motivation? Thesis Motivation could spur you on to push through those tasks during demanding work or study sessions, so you can reach your goals.
Who Should Avoid Thesis Motivation?
Some l-phenylalanine users have experienced side effects like heartburn, nausea, and constipation. You may want to try a different supplement if you have a sensitive stomach.
Motivation was r/crafty_fox9’s favorite product from Thesis because it helped him manage his ADHD. Based on his review, It helped him overcome procrastination, low energy, and a lack of focus [7]. On the company’s website, Samuel S. wrote that he felt that it helped him cognitively, but he experienced some gut issues as well.
Thesis Creativity
Need a spark in your innovative thinking ? Thesis Creativity blends ashwagandha and alpha GPC for their cognitive-boosting effects [12][1]. Together, they could assist you in boosting your brain’s neuroplasticity, cutting down stress, and stimulating your imagination.
Who Is Thesis Creativity Best For?
Artists, writers, or designers who need a boost in creative problem-solving would probably appreciate this supplement. Folks who are neurodivergent may also like Thesis Creativity because it can help them approach tasks from a new perspective.
Who Should Avoid Thesis Creativity?
Given that it comes with caffeine, it might be better to find another alternative to Thesis Creativity if stimulants give you the jitters.
On the company’s website, a lot of customers were genuinely happy with the supplement. Cate P., for example, wrote that it helped organize her thought-process. She explains that she’s already neurodivergent, so she’s creative to begin with. Yet, the supplement helped her regulate that creativity even further.
Some users, like Shannon P., said that, while she appreciated the calm feeling it gave her, she felt quite tired when taking the supplement.
Thesis Confidence
Encouraging you to feel self-assured and more assertive in social and professional settings is the goal of Thesis Confidence. Perhaps that’s why its main ingredient is magnesium; this mineral is known to bolster your mental health while reducing your anxiety, preparing you to confidently face challenges in the office or school [13].
Who Is Thesis Confidence Best For?
Let’s say you have a big presentation or project with a tight deadline and you’re starting to feel butterflies in your stomach. Or, maybe you struggle with social anxiety or often find yourself second-guessing your abilities. Thesis Confidence is ideal for you—ready to boost your self-esteem and help you perform better in high-pressure situations .
Who Should Avoid Thesis Confidence?
Like Creativity, some users wrote that the ingredients in Thesis Confidence made them feel tired rather than made them sharper. You may need a caffeine or energy-booster instead if this is the case.
r/PlateofCreamedCorn wrote that he loved the blend because it made him feel like a cocky version of his normal self [14]. On the other hand, some users on the company’s website claimed that it made them feel drowsy.
Caffeine and L-Theanine
These two ingredients team up to boost your energy and focus. Caffeine and l-theanine perfectly balance each other out: the former for its stimulating effects and the latter for its relaxation [15]. By combining these two components, you have a better chance of being more productive without caffeine jitters.
Who Are Caffeine and L-Theanine Best For?
Do you need a reliable pick-me-up that won’t lead to jitters or an energy crash? This blend can help you stay alert and focused, no matter what project you’re working on.
Who Should Avoid Thesis Caffeine and L-Theanine?
Skip the add-on caffeine if you are sensitive to stimulants or are already suffering from anxiety.
Caffeine and l-theanine are two optional ingredients you can add to your supplements. That’s why they don’t have any specific reviews.
Key Ingredients in Thesis Nootropics
The company makes it a point to include high-quality, research-backed ingredients in all Thesis supplements. Let’s take a look at some of what they use in their blends:
Lion’s Mane
Lion’s mane is a mushroom that’s getting a lot of buzz for its potential to protect and boost your brain. It does this by kickstarting the production of nerve growth factor (NGF) , which is key for keeping your neurons—the cells that your brain uses to send messages to the rest of your body—in tip-top shape [2].
Alpha-GPC is packed with choline and is known to give your brain power a lift. It’s believed to do this by increasing your acetylcholine levels, which has been linked to improving motivation [1].
An amino acid from green tea, l-theanine is known for creating a calm, focused state of mind [11]. When you mix it with caffeine, you may get a perfect combination that can amp up your cognitive performance and mental energy.
Ashwagandha
This adaptogenic herb was used in traditional medicine to help people handle stress and boost brain function. Recent research suggests this herbal ingredient has neuroprotective benefits —meaning it may improve your memory and attention [12].
DHA (Omega-3)
Docosahexaenoic acid (DHA) is an essential omega-3 fatty acid that’s crucial for brain health. Studies have shown it can boost cognitive abilities, particularly in older adults and those with some type of cognitive impairment [16].
Synapsa (Bacopa Monnieri)
This herb is often used in Ayurvedic medicine—one of the oldest medical systems in the world—to improve cognitive function, memory, and learning. One study shows that taking a synapsa supplement improved volunteers’ cognitive abilities when completing a multitasking framework test and reduced cortisol levels [5]. This suggests synapsa can reduce stress, too.
Ginkgo Biloba
Ginkgo biloba is a plant extract known for its potential to improve blood flow and brain function . It’s thought to enhance memory, attention, and processing speed as well [6].
Theacrine is a purine alkaloid similar to caffeine. It’s been studied for boosting energy, focus, and cognitive performance without the crash you often get from caffeine alone [8].
Benefits of Using Thesis Supplements
Here are some of the perks you might experience if you take Thesis nootropics:
Customized Cognitive Improvement
Customers can choose specific blends that cater to their unique cognitive needs and brain chemistry. Not getting the results you want? You can also mix and match dosages—like 50% Creativity and 50% Clarity— so you can make the most of two products.
Improved Focus and Concentration
Many of the blends from Thesis are designed to improve your concentration, attention and mental clarity. On top of this, the helpful effects are meant to last a long time—up to 8 hours for some users.
Enhanced Creativity and Problem-Solving
Some Thesis supplements ingredients target areas like creative thinking, analytical abilities, and brainstorming. If you’re in problem-solving fields of work or need to think through some issues, these supplements can be a great help.
Increased Motivation and Productivity
Lots of over-the-counter nootropics are designed as an alternative to ADHD supporting drugs. If you need a boost in drive, focus, and just productivity overall, some formulas can help you overcome procrastination and stay on task.
Improved Mood and Emotional Well-Being
Need a boost in confidence? Wishing you’d feel less anxious? Some blends from Thesis can support your mental health so you can tackle your day with peace of mind.
Possible Thesis Supplements Side Effects and Contraindications
Thesis nootropics are well-tolerated by most healthy adult users. However, some users reported minor side effects, like:
- Jitteriness or restlessness
- Mild gastrointestinal discomfort
How and When to Use Thesis Supplements
Thesis supplements are quite easy to use. Take a look at these dosage requirements.
Thesis Nootropics Dosage
When it comes to dosing Thesis supplements, it really depends on the blend you’re using and your own personal needs. Generally, it’s best to start with the serving size listed on the product label and tweak it based on how you feel—like taking less if the effects are too strong.
More importantly, you should take the pills consistently since the benefits often build up gradually. Thesis suggests taking these supplements that enhance brain function for at least two to four weeks to see if it’s working for you. Using Thesis supplements regularly at the same time of day helps, too.
Thesis Nootropics Cost
Wondering about the Thesis supplements cost? Well, you’ll have two purchasing options for the Thesis nootropics starter kit:
- One-time purchase: $119
- Subscription: $79 per month
Shipping, Returns, and Refund Policy
Interested in how much the shipping costs will be? If you’re in the US, shipping is free. However, the company currently doesn’t ship to international customers due to challenges with customs regulations.
Thesis also has a 30-day money-back guarantee on all purchases. If you aren’t happy with the Thesis supplements, you can return the unused portion of the product for a full refund, minus any shipping costs.
Where Can You Buy Thesis Supplements?
Thesis supplements are only available on the company’s official website . The brand doesn’t sell its products through third-party retailers or e-commerce platforms.
That way, Thesis can control the quality and authenticity of its supplements. Plus, the company can give personalized recommendations and support to its customers through its one-on-one coaching sessions and quiz-based product recommendations.
Alternatives to Thesis Supplements
While Thesis nootropics offers a unique personalized approach to cognitive enhancement, you might be curious about the other products on the market as well. Check out some of the top competitors in the world of nootropics.
FOCL Daystack
FOCL’s Daystack promises to help you get “in the zone” every day. The supplements’ main ingredients are lion’s mane, vitamin B6, and l-theanine, which combine to promote focus, energy, and memory .
For many, FOCL’s Daystack has helped them feel balanced and focused. The product has a 4.7 out of 5 stars on its website; most reviewers shared that the supplements provided sharper focus and gave them the energy in the morning that lasted through the day.
Some reviewers said they had trouble swallowing the pills though (they are apparently quite large). Plus, certain users complained that their taste was pungent and grassy… but not in a good way. Thankfully, the company offers a variety of products, including gummies and drops.
Mind Lab Pro
Mind Lab Pro combines 11 vegan-friendly ingredients—including lion’s mane mushroom, bacopa monnieri, and B vitamins—that are scientifically supported to help optimize your brain power. From focus, clarity, recall, and overall brain health , these nootropic supplements claim to work in around 30 minutes.
After taking two capsules a day, Reddit user u/acamponea loved how Mind Lab Pro’s supplements helped her get through a long, draining day. She was often surprised at how sharp she felt [17].
Some reviewers, though, said that Mind Lab Pro made them feel drowsy. A Reddit user on r/StackAdvice explained that the supplements helped him get into a good focus zone, but after a few weeks, he started feeling really tired throughout the day [18].
Hunter Focus
Hunter Focus concentrates on improving cognitive performance, mental clarity, and overall brain health. The formula—which leans heavily on citicoline, lion’s mane mushroom, and bacopa monnieri—works together to enhance concentration, memory, and mood .
A Trustpilot reviewer said he is a big fan of Hunter Focus and other Hunter Evolve products. Nevertheless, he mentioned that the delivery was delayed, although the customer support team did a great job in following up the shipping [19].
Noocube’s Brain Productivity supplement only contains scientifically-backed ingredients—like l-theanine, bacopa monnieri, and B vitamins— to help you multitask and sharpen your memory . Plus, the supplement is completely caffeine-free.
One Redditor, r/Spritual_concern932, really appreciates that Noocube’s supplements didn’t make her jittery like stimulants do. She also reported a subtle boost in her focus and mental clarity. However, she did clarify that it wasn’t a magic pill [20].
Addall XR Travel Pack
Addall XR is an over-the-counter substitute for the popular ADHD drug Adderall. The company claims the convenient travel pack includes nutrients to balance dopamine and serotonin creation in your brain, so you can have longer periods of focus and memory.
This supplement showcases a proprietary blend, along with GABA, 1-amino-2-phenylethane, and 2-amino-6-methylheptane. Plus, it’s 100% caffeine free, so it’s not likely to give you jitters or upset your stomach.
Overall, most reviewers were happy with Addall XR. On the company’s website, James L. said that the supplements were great on days when he lacked motivation. The concerns some reviewers had, though, was that they either never got the product after ordering or they got the wrong product.
FAQs on Thesis Supplements
Still got more questions about these nootropics after reading our Thesis reviews? Let’s take a look at the most popular questions and their answers.
Are Thesis Nootropics Worth It?
Yes, Thesis’ personalized approach to cognitive enhancement can be really helpful for people who aren’t sure what nootropics they should take. The quiz and one-on-one coaching—plus customizable supplements—make the company a reliable source of nootropics.
Is Thesis FDA Approved?
Nootropic supplements, such as Thesis nootropics, aren’t subject to the same strict FDA regulation as pharmaceutical drugs. Actually, the FDA doesn’t approve dietary supplements at all, including natural pills for weight loss. However, the FDA does monitor the safety and labeling of these products.
Are Thesis Nootropics Safe?
Yes, Thesis nootropics are generally safe for the majority of healthy users . The company uses natural ingredients that are commonly considered safe—as long as you don’t have an allergy! It’s always a good idea to check the ingredient list and check with your healthcare provider, especially if you take other medications or have health conditions.
How Do Thesis Nootropics Affect the Brain?
When it comes to enhancing mental performance, do Thesis nootropics really work? Yes, Thesis supplements work by combining select natural ingredients that are known to support different brain health and cognitive functions. These nootropics aim to improve your neurotransmitters, increase blood flow to your brain, and reduce oxidative stress.
What Are the Side Effects of Thesis Nootropics?
Though Thesis nootropics are generally well-tolerated, some may have mild side effects. Headaches, digestive issues, or sleep disturbances—especially when first starting out—are the most commonly reported side effects.
How Much Does Thesis Cost per Month?
A subscription to Thesis supplements costs $79 per month.
Does Thesis Work Like Adderall?
Not exactly. While both Thesis and Adderall are designed to boost focus and cognitive function, they do so in different ways . Adderall is a prescription medication with strong stimulants that can have intense effects. Thesis supplements for ADHD use a combination of natural ingredients selected to enhance brain function more gently and sustainably.
Is Thesis Better Than Adderall?
When choosing between Thesis nootropics vs Adderall, it really depends on what you’re looking for. Adderall is a prescription medication typically used for ADHD. While it strongly boosts focus and energy, it can have major side effects. Thesis nootropics are made from natural ingredients, so its benefits are subtler than Adderall yet it has a lower risk of adverse effects, too.
Final Note on Thesis Supplements
Have you tried nootropic supplements that just haven’t lived up to the promises on their label? You may need a more personalized approach to your brain health .
Thesis supplements are customized to meet your cognitive needs—whether you’re hoping to optimize your mental health or just want a boost for those unmotivated days. Take Thesis’s quiz and see what products fit your goals.
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